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The provided text details MOTS-C (Mitochondrial Orphan Peptide), a short regulatory peptide that has gained notoriety for its potential benefits related to metabolic health, physical performance, and anti-aging.1
| Feature | Detail |
| Active Substance | MOTS-C (Mitochondrial Orphan Peptide) |
| Encoded Substance | 12S rRNA-c, MT-RNR1 |
| Manufacturer | Driada Medical EU |
| Concentration | 10 mg/vial |
| Presentation | 1 vial |
| Classification | Mitochondrial-Encoded Regulatory Peptide |
MOTS-C is a short regulatory peptide encoded in the mitochondrial genome.2 It is crucial for mitochondrial function and cellular metabolism.
Mechanism: It controls metabolism by modulating important metabolic pathways involved in energy production, glucose metabolism, and insulin sensitivity.3
Administration: Generally administered by subcutaneous injection.4
MOTS-C holds potential for use in several areas:
| Potential Benefit | Mechanism/Target |
| Improved Metabolic Health | Increases mitochondrial function, energy expenditure, and glucose metabolism. Potentially beneficial for obesity and Type 2 Diabetes. |
| Enhanced Physical Performance | Augments energy production and muscle performance, improving endurance, strength, and recovery for athletes and fitness enthusiasts. |
| Anti-Aging Effects | Linked to regulating aging processes through maintenance of mitochondrial function and cellular health. |
| Neuroprotection | Early studies suggest potential neuroprotective attributes, possibly protecting against neurodegenerative conditions (Alzheimer's, Parkinson's). |
Primary Targets: Mitochondria (regulating energy production), Metabolic Pathways (glucose metabolism, insulin sensitivity), and Muscle Tissue (enhancing strength and endurance).5
Dosage: The optimum dose is still yet to be established as experiments are ongoing. Researchers have used dosages ranging from micrograms to milligrams injected subcutaneously.
Side Effects (Generally Well-Tolerated): Injection site reactions, allergic reactions, and gastrointestinal upset.
Precaution: A great deal more investigation must be completed to entirely understand its long-term safety profile. Consultation with a healthcare professional is recommended before use.
1. Where is the MOTS-C peptide encoded in the body?
MOTS-C is a unique peptide because it is encoded in the mitochondrial genome, not the nuclear genome, highlighting its crucial role in mitochondrial function and energy.
2. How does MOTS-C help with potential metabolic disorders?
It helps by increasing mitochondrial function, enhancing energy expenditure, and improving glucose metabolism and insulin sensitivity.6
3. Why is MOTS-C of interest to fitness enthusiasts and athletes?
It is of interest because supplementation is thought to augment physical performance by increasing energy production, muscle function, strength, endurance, and recovery.7
4. What is the standard method of administering MOTS-C?
MOTS-C is generally administered by subcutaneous injection.8
